The 
San Francisco 49ers continue to battle the injury bug, and they’ll now be without their star tight end for their Week 4 matchup against the 
Los Angeles Ramson Sunday afternoon
Tight end George Kittle has been ruled OUT for Week 4, according to the 49ers.
The 49ers will now be without star RB Christian McCaffrey for at least four weeks, Deebo Samuel also ruled out for Week 3, and now their no.1 tight end is out for at least this week.
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