After a busy week of European action, Spain’s top clubs return to domestic matters this weekend. The Basque derby tops the bill on Sunday, as Athletic Club play host to Real Sociedad at San Mames.
Here are our LaLiga predicted lineups for matchday 22. All kick-offs are based on the local time in Spain. Players in bold are those considered to have the highest chance of starting (80% or more).
LaLiga predicted lineups – Matchday 22

Friday 30th January 2026
21:00 – Espanyol vs Alaves
Espanyol predicted lineup
Dmitrovic – Romero, Cabrera, Calero, El Hilali – Terrats, Exposito, Gonzalez de Zarate, Dolan – K. Garcia, R. Fernandez (4-4-2)
Alaves predicted lineup
Sivera – Castro, Pacheco, Benavidez, Jonny – Aleña, Ibañez, Blanco, Calebe – T. Martinez, Boye (4-4-2)

Saturday 31st January 2026
14:00 – Real Oviedo vs Girona
Real Oviedo predicted lineup
Escandell – J. Lopez, Carmo, Costas, Vidal – Colombatto, Sibo – Chaira, Reina, Hassan – Viñas (4-2-3-1)
Girona predicted lineup
Ter Stegen – Moreno, Blind, Reis, A. Martinez – Martin, Witsel, Lemar – Gil, Vanat, Tsygankov (4-3-3)
16:15 – Osasuna vs Villarreal
Osasuna predicted lineup
Herrera – Galan, Catena, Boyomo, Rosier – Moncayola, Torro – Ruben Garcia, M. Gomez, Muñoz – Budimir (4-2-3-1)
Villarreal predicted lineup
Junior – Pedraza, Veiga, Marin, Mouriño – Moleiro, Gueye, Parejo, Buchanan – G. Moreno, Mikautadze (4-4-2)
18:30 – Levante vs Atletico Madrid
Levante predicted lineup
Ryan – M. Sanchez, Matturo, De la Fuente, Toljan – P. Martinez, Raghouber – Losada, C. Alvarez, Romero – Etta Eyong (4-2-3-1)
Atletico Madrid predicted lineup
Oblak – Ruggeri, Hancko, Pubill, Llorente – Almada, Barrios, Cardoso, Simeone – Sorloth, Alvarez (4-4-2)
21:00 – Elche vs Barcelona
Elche predicted lineup
Peña – Petrot, Affengruber, Chust – Valera, Neto, Aguado, Mendoza, Pedrosa – Diangana, A. Rodriguez (3-5-2)
Barcelona predicted lineup
J. Garcia – Balde, Martin, Cubarsi, Kounde – E. Garcia, De Jong – Raphinha, Fermin, Yamal – Ferran (4-2-3-1)

Sunday 1st February 2026
14:00 – Real Madrid vs Rayo Vallecano
Real Madrid predicted lineup
Courtois – Carreras, Huijsen, Asencio, Valverde – Tchouameni, Guler – Vinicius, Bellingham, Rodrygo – Mbappe (4-2-3-1)
Rayo Vallecano predicted lineup
Batalla – Chavarria, Mendy, Lejeune, Balliu – Ciss, U. Lopez – A. Garcia, Palazon, Akhomach – De Frutos (4-2-3-1)
16:15 – Real Betis vs Valencia
Real Betis predicted lineup
Valles – Rodriguez, Llorente, Bartra, Ruibal – Roca, Altimira – Ez, Fornals, Antony – Bakambu (4-2-3-1)
Valencia predicted lineup
Dimitrievski – Gaya, Copete, Comert, Foulquier – Pepelu, Ugrinic – Danjuma, Beltran, Rioja – Duro (4-2-3-1)
18:30 – Getafe vs Celta Vigo
Getafe predicted lineup
Soria – Iglesias, Romero, Djene, Duarte, Femenia – Martin, Arambarri, Milla – Vazquez, Satriano (5-3-2)
Celta Vigo predicted lineup
Radu – Dominguez, Starfelt, J. Rodriguez – Mingueza, Moriba, Sotelo, Carreira – Zaragoza, Swedberg – Iglesias (3-4-2-1)
21:00 – Athletic Club vs Real Sociedad
Athletic Club predicted lineup
Simon – Yuri, Laporte, Paredes, Areso – Jauregizar, Ruiz de Galarreta – N. Williams, Navarro, Berenguer – Guruzeta (4-2-3-1)
Real Sociedad predicted lineup
Remiro – Gomez, Zubeldia, Martin, Aramburu – Gorrotxategi, Turrientes – Barrenetxea, Soler, Guedes – Oyarzabal (4-2-3-1)
Monday 2nd February 2026
21:00 – Mallorca vs Sevilla
Mallorca predicted lineup
Roman – Mojica, D. Lopez, Valjent, Maffeo – S. Costa, Mascarell – Virgili, Darder, Joseph – Muriqi (4-2-3-1)
Sevilla predicted lineup
Vlachodimos – Salas, Castrin, Carmona – Suazo, Sow, Agoume, Juanlu – Peque – Romero, Adams (3-4-1-2)
Mark is a freelance football writer based in Madrid, and the editor of LaLigaExpert.com. He has been covering LaLiga and European football since 2014.