LaLiga 2025/26 matchday 16 predicted lineups

After Celta Vigo stunned Real Madrid at the Bernabeu last weekend, Barcelona have a four-point lead at the top of La Liga. They hosts Osasuna on Saturday, so the pressure is likely to be on Los Blancos when they travel to Vitoria on Sunday night.

Here are our LaLiga predicted lineups for matchday 16. All kick-off times are based on the local time in Spain. Players in bold are those considered to have the highest chance of starting (80% or more).

LaLiga predicted lineups – Matchday 16

Friday 12th December 2025

21:00 – Real Sociedad vs Girona

Real Sociedad predicted lineup

Remiro – Gomez, Martin, Zubeldia, Aramburu – Soler, Gorrotxategi, B. Mendez – Barrenetxea, Guedes, Kubo (4-3-3)

Girona predicted lineup

Gazzaniga – Moreno, Blind, Reis, A. Martinez – Martin, Witsel, Ounahi – Gil, Vanat, Tsygankov (4-3-3)

Saturday 13th December 2025

14:00 – Atletico Madrid vs Valencia

Atletico Madrid predicted lineup

Oblak – Ruggeri, Lenglet, Le Normand, Molina – N. Gonzalez, Barrios, Cardoso, Simeone – Sorloth, Alvarez (4-4-2)

Valencia predicted lineup

Agirrezabala – Gaya, Copete, Comert, Foulquier, Correia – Danjuma, Pepelu, Ugrinic, Rioja – Duro (5-4-1)

16:15 – Mallorca vs Elche

Mallorca predicted lineup

Bergstrom – Mojica, Kumbulla, Valjent, Maffeo – Mascarell, Morlanes – Virgili, Darder, Joseph – Muriqi (4-2-3-1)

Elche predicted lineup

Peña – Bigas, Affengruber, Chust  – Valera, Febas, Aguado, Nuñez, Fort – Mir, A. Rodriguez (3-5-2)

18:30 – Barcelona vs Osasuna

Barcelona predicted lineup

J. Garcia – Balde, E. Garcia, Cubarsi, Kounde – Pedri, De Jong – Raphinha, Fermin, Yamal – Ferran (4-2-3-1)

Osasuna predicted lineup

Herrera – Bretones, Catena, Boyomo, Rosier – Moncayola, Torro – Ruben Garcia, Oroz, V. Muñoz – Raul Garcia (4-2-3-1)

21:00 – Getafe vs Espanyol

Getafe predicted lineup

Soria – Nyom, Djene, Duarte, Iglesias, Femenia – Martin, Arambarri, J. Muñoz – Liso, Mayoral (5-3-2)

Espanyol predicted lineup

Dmitrovic – Romero, Cabrera, Calero, El Hilali – Exposito, Gonzalez de Zarate, Lozano – Milla, R. Fernandez, Jofre (4-3-3)

Sunday 14th December 2025

14:00 – Sevilla vs Real Oviedo

Sevilla predicted lineup

Vlachodimos – Oso, Gudelj, Castrin, Carmona – Agoume, Mendy – Alfon, Sow, Alexis – Adams (4-2-3-1)

Real Oviedo predicted lineup

Escandell – Alhassane, Carmo, Costas, Vidal – Colombatto, Dendoncker – Chaira, Reina, Hassan – Rondon (4-2-3-1)

16:15 – Celta Vigo vs Athletic Club

Celta Vigo predicted lineup

Radu – Alonso, Starfelt, M. Fernandez – Mingueza, Roman, Sotelo, Rueda – Zaragoza, Aspas – Iglesias (3-4-2-1)

Athletic Club predicted lineup

Simon – Yuri, Paredes, Vivian, Gorosabel – Jauregizar, Ruiz de Galarreta – N. Williams, Sancet, Berenguer – Guruzeta (4-2-3-1)

18:30 – Levante vs Villarreal

Levante predicted lineup

Ryan – M. Sanchez, Matturro, Cabello, Toljan – Brugui, Vencedor, Arriaga, C. Alvarez – Etta Eyong, Romero (4-4-2)

Villarreal predicted lineup

Junior – Cardona, Veiga, Foyth, Navarro – Moleiro, Comesaña, Parejo, Akhomach – A. Perez, Oluwaseyi (4-4-2)

21:00 – Alaves vs Real Madrid

Alaves predicted lineup

Sivera – Parada, Pacheco, Tenaglia, Jonny – Ibañez, Blanco – Rebbach, D. Suarez, Calebe – Boye (4-1-3-2)

Real Madrid predicted lineup

Courtois – Camavinga, Rudiger, Asencio, Valverde – Guler, Tchouameni, Bellingham – Vinicius, G. Garcia, Rodrygo (4-3-3)

Monday 15th December 2025

21:00 – Rayo Vallecano vs Real Betis

Rayo Vallecano predicted lineup

Batalla – Chavarria, Mendy, Lejeune, Ratiu – Valentin, Ciss – A. Garcia, I. Palazon, F. Perez – De Frutos (4-2-3-1)

Real Betis predicted lineup

 P. Lopez – Rodriguez, Natan, Bartra, Ruibal – Roca, Fornals – Riquelme, Lo Celso, Antony – C. Hernandez (4-2-3-1)

Mark is a freelance football writer based in Madrid, and the editor of LaLigaExpert.com. He has been covering LaLiga and European football since 2014.